Chlorine carries a negative charge (anion). It is found in blood and the body's cells. In fact, it is the most abundant anion found in the body. Blood chlorine levels are closely regulated through various mechanisms. Chlorine plays several roles in the body. It is strongly linked with blood sodium, which carries a positive charge. It plays an important role in blood pressure in blood vessels and cells. It is involved in the acid-base equilibrium.
If the result is too high
High chloride levels are found in dehydrated patients or those with an acid-base imbalance in the blood.
If the result is too low
Kidney problems, such as kidney impairment, can result in lower values. Loss of chloride due to vomiting will also result in lower levels. Acid-base imbalance and heart failure can both translate into lower levels.
Intravenous fluid replacement can increase chloride levels. Some drugs, such as cholestyramine and phenylbutazone, can also increase chloride levels.
Taking certain drugs, such as thiazide diuretics, ethacrynic acid, furosemide or prolonged IV dextrose infusion, can lower blood chloride levels.
What you need to know before the test
Before going for blood tests, a procedure or other exam, it is best to always bring a list of all the drugs you take (prescription, OTC and natural health products). Unless told otherwise, you should take your medication as usual on the day of the test. When in doubt, ask your pharmacist for more information.
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The patient information leaflets are provided by Vigilance Santé Inc. This content is for information purposes only and does not in any manner whatsoever replace the opinion or advice of your health care professional. Always consult a health care professional before making a decision about your medication or treatment.